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TISSUE AND ORGAN ENGINEERING

Research in this area involves generation of tissue-tissue interfaces and complex tissues/organs using functionally graded devices. Demand for the repair or replacement of tissues/organs is increasing at a higher rate, since organ transplantation is strictly restricted by donor shortages and immuno-complications. At this point, tissue engineering emerges as a promising approach given the recent developments in the efforts of engineering of very diverse tissues.

Tissue-tissue interfaces are comprised of diverse tissues, and they are not homogeneous yet graded in terms of function, structure and composition. Therefore, a scaffold/device to be utilized for the engineering of interface tissues should exhibit such structures inherently for the better mimicking of their native counterparts, and design and fabrication of functionally graded materials plays a significant role at this point.